LUSH Shapes Up for a Starring Role in Olfaction
نویسندگان
چکیده
In the fruit fly Drosophila, odorant-binding proteins are secreted into the fluid that bathes olfactory neurons. Laughlin et al. (2008) now challenge the assumption that the odorant-binding protein LUSH passively transports its pheromone to a specific olfactory receptor. Instead, LUSH undergoes a conformational change upon pheromone binding that is sufficient for neuronal activation.
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ورودعنوان ژورنال:
- Cell
دوره 133 شماره
صفحات -
تاریخ انتشار 2008